Detalhe da pesquisa
1.
A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function.
Nat Immunol
; 24(4): 676-689, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36914891
2.
Mechanobiology of T Cell Activation: To Catch a Bond.
Annu Rev Cell Dev Biol
; 37: 65-87, 2021 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34213954
3.
Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.
Cell
; 174(3): 672-687.e27, 2018 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30053426
4.
A TCR mechanotransduction signaling loop induces negative selection in the thymus.
Nat Immunol
; 19(12): 1379-1390, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420628
5.
Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling.
Cell
; 157(2): 357-368, 2014 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24725404
6.
Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition.
Mol Cell
; 73(5): 1015-1027.e7, 2019 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30711376
7.
What's the Catch? The Significance of Catch Bonds in T Cell Activation.
J Immunol
; 211(3): 333-342, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37459191
8.
Immunogen-Specific Strengths and Limitations of the Activation-Induced Marker Assay for Assessing Murine Antigen-Specific CD4+ T Cell Responses.
J Immunol
; 210(7): 916-925, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36883856
9.
An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes.
Biochemistry
; 59(43): 4163-4175, 2020 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33074657
10.
MHC Bias by T Cell Receptors: Genetic Evidence for MHC and TCR Coevolution.
Trends Immunol
; 38(1): 2-4, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27939452
11.
Two-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discrimination.
Immunity
; 34(1): 13-23, 2011 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21256056
12.
Force in Immunology: There Is Often a Catch.
J Immunol
; 211(3): 307, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37459188
13.
CD4 T Cell Affinity Diversity Is Equally Maintained during Acute and Chronic Infection.
J Immunol
; 201(1): 19-30, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29777029
14.
Relationship of 2D Affinity to T Cell Functional Outcomes.
Int J Mol Sci
; 21(21)2020 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33120989
15.
Understanding TCR affinity, antigen specificity, and cross-reactivity to improve TCR gene-modified T cells for cancer immunotherapy.
Cancer Immunol Immunother
; 68(11): 1881-1889, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31595324
16.
NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease.
J Immunol
; 199(8): 2680-2691, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28887429
17.
Conserved Region C Functions To Regulate PD-1 Expression and Subsequent CD8 T Cell Memory.
J Immunol
; 198(1): 205-217, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27895178
18.
Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.
Cancer Immunol Immunother
; 67(2): 311-325, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29052782
19.
Correction to: Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.
Cancer Immunol Immunother
; 67(2): 327, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29264697
20.
Low-Affinity Memory CD8+ T Cells Mediate Robust Heterologous Immunity.
J Immunol
; 196(6): 2838-46, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26864034